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SC-2001

Product Specifications

CAS Number

1383727-17-0

Target

Others, STAT, Apoptosis, Bcl-2 Family

Related Pathways

Stem Cells, JAK/STAT signaling, Apoptosis, Others

Bioactivity

SC-2001 is a MCL-1 inhibitor. SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma.

Smiles

C(C=1NC(C2=CC=3C(N2)=CC=C(Br)C3)=CC1OC)=C4C=CC=N4

Molecular Formula

C18H14BrN3O

Molecular Weight

368.23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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