SB-747651A

Product Specifications

CAS Number

607372-46-3

Target

Others|||p38 MAPK

Related Pathways

MAPK|||Others

Bioactivity

SB-747651A is a potent, ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1, IC50 = 11 nM) . It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells.

Smiles

C(C)N1C=2C(N=C1C=3C(N)=NON3)=CN=CC2CNC4CCNCC4

Molecular Formula

C16H22N8O

Molecular Weight

342.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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