SB-747651A
Product Specifications
CAS Number
607372-46-3
Target
Others|||p38 MAPK
Related Pathways
MAPK|||Others
Bioactivity
SB-747651A is a potent, ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1, IC50 = 11 nM) . It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells.
Smiles
C(C)N1C=2C(N=C1C=3C(N)=NON3)=CN=CC2CNC4CCNCC4
Molecular Formula
C16H22N8O
Molecular Weight
342.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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