Sarmustine
Product Specifications
CAS Number
81965-43-7
Target
DNA Methyltransferase, DNA Alkylation, Apoptosis, DNA Alkylator/Crosslinker, p53
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
Sarmustine (SarCNU) is an alkylating agent with anticancer activity that inhibits the growth of prostate cancer cells via p53-dependent and p53-independent pathways.Sarmustine mediates the selection of P140K methylguanine-DNA-methyltransferase-transduced human CD34 (+) cells in vitro.
Smiles
C(N(CCCl)N=O)(N(CC(N)=O)C)=O
Molecular Formula
C6H11ClN4O3
Molecular Weight
222.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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