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Ex26

Product Specifications

CAS Number

1233332-37-0

Target

LPL Receptor, S1P Receptor

Related Pathways

GPCR/G Protein

Purity

0.9962

Bioactivity

Ex26 (S1P1-IN-Ex26) is a selective and potent sphingosine 1-phosphate receptor 1 (S1P1) antagonist that disrupts SR-B1-S1PR1 interactions and inhibits S1P-S1PR1 signaling. Ex26 is used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.

Smiles

O=C(O)C1(NC(=O)C2=C(C=C(C=C2C)C=3C=C(C=CC3F)NC(C4=CC=C(Cl)C(=C4)C)C)C)CC1

Molecular Formula

C28H28ClFN2O3

Molecular Weight

494.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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