Ex26
Product Specifications
CAS Number
1233332-37-0
Target
LPL Receptor, S1P Receptor
Related Pathways
GPCR/G Protein
Purity
0.9962
Bioactivity
Ex26 (S1P1-IN-Ex26) is a selective and potent sphingosine 1-phosphate receptor 1 (S1P1) antagonist that disrupts SR-B1-S1PR1 interactions and inhibits S1P-S1PR1 signaling. Ex26 is used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.
Smiles
O=C(O)C1(NC(=O)C2=C(C=C(C=C2C)C=3C=C(C=CC3F)NC(C4=CC=C(Cl)C(=C4)C)C)C)CC1
Molecular Formula
C28H28ClFN2O3
Molecular Weight
494.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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