RX-37
Product Specifications
CAS Number
1627715-60-9
Target
Others, Epigenetic Reader Domain
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
RX-37 is a potent BET inhibitor with Ki values of 3.2-24.7 nM for BRD2, BRD3 and BRD4. RX-37 demonstrates high selectivity over other non-BET bromodomain-containing proteins. RX-37 potently and selectively inhibits cell growth in human acute leukemia cell lines harboring the rearranged mixed lineage leukemia 1 gene.
Smiles
CC1=C(C2=C3C=4C(NC3=CC=N2)=CC(=C(OC)C4)C=5C(C)=NOC5C)C(=NN1)C6CC6
Molecular Formula
C24H23N5O2
Molecular Weight
413.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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