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RX-37

Product Specifications

CAS Number

1627715-60-9

Target

Others, Epigenetic Reader Domain

Related Pathways

Others, Chromatin/Epigenetic

Bioactivity

RX-37 is a potent BET inhibitor with Ki values of 3.2-24.7 nM for BRD2, BRD3 and BRD4. RX-37 demonstrates high selectivity over other non-BET bromodomain-containing proteins. RX-37 potently and selectively inhibits cell growth in human acute leukemia cell lines harboring the rearranged mixed lineage leukemia 1 gene.

Smiles

CC1=C(C2=C3C=4C(NC3=CC=N2)=CC(=C(OC)C4)C=5C(C)=NOC5C)C(=NN1)C6CC6

Molecular Formula

C24H23N5O2

Molecular Weight

413.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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