Daphnetin
Product Specifications
CAS Number
486-35-1
Target
PKC, ROS, PKA, AMPK, Autophagy, EGFR, mTOR, Parasite, Reactive Oxygen Species, Apoptosis, PARP, Caspase, Bcl-2 Family, Akt
Related Pathways
PI3K/Akt/mTOR signaling, NF-κB, Proteases/Proteasome, Tyrosine Kinase/Adaptors, Microbiology/Virology, Immunology/Inflammation, Autophagy, Chromatin/Epigenetic, Metabolism, Cytoskeletal Signaling, JAK/STAT signaling, DNA Damage/DNA Repair, Apoptosis, Angiogenesis
Purity
0.9982
Bioactivity
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.
Smiles
Oc1ccc2ccc(=O)oc2c1O
Molecular Formula
C9H6O4
Molecular Weight
178.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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