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R-84760 hydrochloride

Product Specifications

CAS Number

157824-23-2

Target

Others, Opioid Receptor

Related Pathways

Others, GPCR/G Protein, Neuroscience, Endocrinology/Hormones

Bioactivity

R-84760 is a κ-opioid receptor agonist. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in the central nervous system; and a part of the mechanism of the antinociceptive effect of R-84760 is activation of the descending noradrenergic pathway.

Smiles

C(=O)([C@@H]1C=2C(CC1)=CC(Cl)=C(Cl)C2)N3[C@H](CN4CCCC4)CSCC3.Cl

Molecular Formula

C19H25Cl3N2OS

Molecular Weight

435.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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