Pyrazoloacridine
Product Specifications
CAS Number
99009-20-8
Target
Topoisomerase, Apoptosis
Related Pathways
Apoptosis, DNA Damage/DNA Repair
Purity
0.9972
Bioactivity
Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.
Smiles
COc1ccc2[nH]c3c(ccc4n(CCCN(C)C)nc(c34)c2c1)[N+]([O-])=O
Molecular Formula
C19H21N5O3
Molecular Weight
367.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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