PHPS1
Product Specifications
CAS Number
314291-83-3
Target
Phosphatase
Related Pathways
Metabolism
Purity
0.9977
Bioactivity
PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.
Smiles
OS(=O)(=O)c1ccc(N\N=C2/C(=O)N(N=C2c2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1
Molecular Formula
C21H15N5O6S
Molecular Weight
465.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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