PHPS1

Product Specifications

CAS Number

314291-83-3

Target

Phosphatase

Related Pathways

Metabolism

Purity

0.9977

Bioactivity

PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.

Smiles

OS(=O)(=O)c1ccc(N\N=C2/C(=O)N(N=C2c2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1

Molecular Formula

C21H15N5O6S

Molecular Weight

465.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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