PF-6422899
Product Specifications
CAS Number
1621002-23-0
Target
Others, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Others, Angiogenesis, JAK/STAT signaling
Bioactivity
PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.
Smiles
N(C=1C2=C(C=C(OCC#C)C(NC(C=C)=O)=C2)N=CN1)C3=CC(Cl)=C(F)C=C3
Molecular Formula
C20H14ClFN4O2
Molecular Weight
396.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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