PF-06278121
Product Specifications
CAS Number
1402438-37-2
Target
Others, Trk receptor
Related Pathways
Others, Tyrosine Kinase/Adaptors
Bioactivity
PF-06278121 is a potent and selective Trk inhibitor. PF-06278121 shows Trk A/B IC50 = 4/94 nM (enzymatic assay), Trk A/B/C IC50 = 13/7/6 nM (PathHunter cell assay) .
Smiles
C(=O)(C=1C=2C(N([C@H](CO)C)C1)=NC=NC2)C=3C=C(NC(CC4=CC=C(C(F)(F)F)C=C4)=O)C=NC3
Molecular Formula
C24H20F3N5O3
Molecular Weight
483.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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