PD-89211
Product Specifications
CAS Number
444725-49-9
Target
Dopamine Receptor, Others
Related Pathways
Neuroscience, Others, GPCR/G Protein
Bioactivity
PD 89211 is a selective dopamine D4 receptor antagonist with high selectivity for the DA D4.2 receptor (> 800-fold) as compared to other hDA receptor subtypes, rat brain serotonin, and adrenergic receptors. In vitro, PD 89211 reverses quinpirole-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM) .
Smiles
C(C=1NC=2C(N1)=CC=CC2)N3CCN(CC3)C4=CC(Cl)=C(CO)C=C4
Molecular Formula
C19H21ClN4O
Molecular Weight
356.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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