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PD-89211

Product Specifications

CAS Number

444725-49-9

Target

Dopamine Receptor|||Others

Related Pathways

Neuroscience|||Others|||GPCR/G Protein

Bioactivity

PD 89211 is a selective dopamine D4 receptor antagonist with high selectivity for the DA D4.2 receptor (> 800-fold) as compared to other hDA receptor subtypes, rat brain serotonin, and adrenergic receptors. In vitro, PD 89211 reverses quinpirole-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM) .

Smiles

C(C=1NC=2C(N1)=CC=CC2)N3CCN(CC3)C4=CC(Cl)=C(CO)C=C4

Molecular Formula

C19H21ClN4O

Molecular Weight

356.85

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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