PD 122860
Product Specifications
CAS Number
122576-86-7
Target
Calcium Channel, Sodium Channel, Others
Related Pathways
Membrane transporter/Ion channel, Others, Metabolism
Bioactivity
PD 122860 is a dihydropyridine with calcium channel blocking and sodium channel stimulating properties. In the rat heart, PD 122860 increased left ventricular contractility, decreased coronary resistance and altered the shape of the electrocardiogram T-wave. PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes.
Smiles
C(OCC)(=O)C=1C(C(C#N)=C(C)NC1CS(=O)(=O)C=2C=CN=CC2)C3=C(C(F)(F)F)C=CC=C3
Molecular Formula
C23H20F3N3O4S
Molecular Weight
491.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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