OXA-11
Product Specifications
CAS Number
1257994-15-2
Target
FAK
Related Pathways
Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Purity
0.992
Bioactivity
OXA-11 (FAK-IN-16) is an orally active, selective focal adhesion kinase (FAK) inhibitor with antitumor activity. It inhibits FAK phosphorylation at tyrosine 397 in a dose-dependent manner and suppresses TOV21G tumor growth. It is used in cancer research.
Smiles
N(C1=C2C(=C(C=C1)[C@H]3CC[C@@H](CC3)N4CCN(C)CC4)CN(C)C2=O)C=5C(C(F)(F)F)=CN=C(NC6=C(OC)C=C(CP(OCC)(OCC)=O)C=C6)N5
Molecular Formula
C37H49F3N7O5P
Molecular Weight
759.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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