OSI-296
Product Specifications
CAS Number
1175296-94-2
Target
C-Met/HGFR|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Others
Bioactivity
OSI-296 is a potent and dual inhibitor of cMET and RON kinases (IC50 value are 42 nM and 200 nM for cMet and sfRon respectively) . OSI-206 shows in vivo efficacy and is well tolerated in tumor xenografts models upon oral dosing. OSI-296 also reduces tumour growth in the bone.
Smiles
O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=C3C(C(=CO3)C=4CCN(C(N)=O)CC4)=CN=C2N
Molecular Formula
C21H19Cl2FN4O3
Molecular Weight
465.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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