ONO-8809
Product Specifications
CAS Number
123288-47-1
Target
Others, Histamine Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Neuroscience, Others
Bioactivity
ONO-8809 is a thromboxane A2 receptor antagonist. ONO-8809 inhibited the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner. Macrophage accumulation and matrix metalloproteinase-9 (MMP-9) activity in the stroke-negative area in the contralateral cerebral cortex to the stroke lesion of salt-loaded SHRSP and 8-iso-PGF2alpha-treated SHRSP were significantly reduced by ONO-8809 treatment.
Smiles
C(NS(=O)(=O)C1=CC=C(Br)C=C1)[C@H]2[C@H](/C=C\CCCC(OCCCCCCCCCC)=O)[C@@]3(C[C@]2(CC3)[H])[H]
Molecular Formula
C30H46BrNO4S
Molecular Weight
596.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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