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NNC052090

Product Specifications

CAS Number

184845-43-0

Target

Others, GABA Receptor

Related Pathways

Membrane transporter/Ion channel, Others, Neuroscience

Bioactivity

NNC052090 is a GABA uptake inhibitor that displays moderate selectivity for BGT-1 transporters with Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively. NNC052090 also displays affinity at α1- and D2-receptors with IC50 values are 266 and 1632 nM respectively.

Smiles

C(CCN1CCC(O)(CC1)C2=C(OC)C=CC=C2)N3C=4C(C=5C3=CC=CC5)=CC=CC4

Molecular Formula

C27H30N2O2

Molecular Weight

414.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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