NMK-TD-100
Product Specifications
CAS Number
1252802-38-2
Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Apoptosis, Others
Bioactivity
NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 μM.
Smiles
O(C)C=1C=C(C=2SC(C=3C=4C(NC3)=CC=CC4)=NN2)C=C(OC)C1OC
Molecular Formula
C19H17N3O3S
Molecular Weight
367.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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