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NMK-TD-100

Product Specifications

CAS Number

1252802-38-2

Target

Apoptosis|||Others|||Microtubule Associated

Related Pathways

Cytoskeletal Signaling|||Apoptosis|||Others

Bioactivity

NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 µM.

Smiles

O(C)C=1C=C(C=2SC(C=3C=4C(NC3)=CC=CC4)=NN2)C=C(OC)C1OC

Molecular Formula

C19H17N3O3S

Molecular Weight

367.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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