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NLRP3-IN-9

Product Specifications

CAS Number

88039-46-7

Target

NOD, NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation, NF-κB

Purity

0.9964

Bioactivity

NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

Smiles

CCOC(=O)C(=C)C(O)c1ccccc1Cl

Molecular Formula

C12H13ClO3

Molecular Weight

240.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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