NLRP3-IN-9
Product Specifications
CAS Number
88039-46-7
Target
NOD|||NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation|||NF-?B
Purity
0.9964
Bioactivity
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
Smiles
CCOC(=O)C(=C)C(O)c1ccccc1Cl
Molecular Formula
C12H13ClO3
Molecular Weight
240.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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