NGB 2904
Product Specifications
CAS Number
189060-98-8
Target
Dopamine Receptor|||5-HT Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Purity
0.9935
Bioactivity
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, ?1, D4, D1 and D5 receptors respectively) . NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM) .
Smiles
Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl
Molecular Formula
C28H29Cl2N3O
Molecular Weight
494.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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