NF-1819
Product Specifications
CAS Number
1881244-28-5
Target
MAGL, Lipase
Related Pathways
Metabolism
Purity
0.9955
Bioactivity
NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. NF-1819 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. NF-1819 displays high membrane permeability and brain penetrant.
Smiles
[H][C@@]1(N(C2CCN(CC2)C(=O)n2cncn2)C(=O)[C@]1([H])c1ccc(F)cc1)c1ccc2OCOc2c1
Molecular Formula
C24H22FN5O4
Molecular Weight
463.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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