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NEU-1045

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

NEU-1045 is a T. brucei proliferation inhibitor, and is a promising lead with cross-pathogen activity. NEU-1045 inhibited T. brucei, T. cruzi, and L. major proliferation with good potency (T. brucei EC50 = 0.37 ?M; T. cruzi EC50 = 2.8 ?M; L. major EC50 = 1.2 ?M) .

Smiles

FC1=CC(COC(C=C2)=CC=C2NC3=CC=NC(C3=C4)=CC=C4C5=CC=C(S(N6CCOCC6)(=O)=O)C=C5)=CC=C1

Molecular Formula

C32H28FN3O4S

Molecular Weight

569.65

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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