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MRS2179

Product Specifications

CAS Number

101204-49-3

Target

P2Y Receptor|||Others

Related Pathways

Others|||Neuroscience|||GPCR/G Protein

Bioactivity

MRS2179 is a competitive P2Y1 receptor antagonist (Kb = 100 nM) with no appreciable activity at P2Y2, P2Y4, or P2Y6 at concentrations up to 30 µM, or at P2Y12 and P2Y13. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls.

Smiles

N(C)C1=C2C(N(C=N2)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](OP(=O)(O)O)C3)=NC=N1

Molecular Formula

C11H17N5O9P2

Molecular Weight

425.23

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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