MRS2179
Product Specifications
CAS Number
101204-49-3
Target
P2Y Receptor|||Others
Related Pathways
Others|||Neuroscience|||GPCR/G Protein
Bioactivity
MRS2179 is a competitive P2Y1 receptor antagonist (Kb = 100 nM) with no appreciable activity at P2Y2, P2Y4, or P2Y6 at concentrations up to 30 µM, or at P2Y12 and P2Y13. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls.
Smiles
N(C)C1=C2C(N(C=N2)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](OP(=O)(O)O)C3)=NC=N1
Molecular Formula
C11H17N5O9P2
Molecular Weight
425.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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