MLN-3897
Product Specifications
CAS Number
1010731-97-1
Target
CCR
Related Pathways
Microbiology/Virology, Immunology/Inflammation, GPCR/G Protein
Purity
0.9862
Bioactivity
MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.
Smiles
C(CCN1CC(C)(C)[C@](O)(CC1)C2=CC=C(Cl)C=C2)=C3C=4C(OCC=5C3=CC=CN5)=CC=C(C(O)=O)C4
Molecular Formula
C30H31ClN2O4
Molecular Weight
519.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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