MGS-0039
Product Specifications
CAS Number
569686-87-9
Target
GluR, Others
Related Pathways
Neuroscience, Others
Bioactivity
MGS-0039 is a group II metabotropic glutamate receptor (mgluR2/3) antagonist. Antidepressant-like action of group II mGlu receptor antagonists does not depend on serotonergic system activation. However, the AMPA receptor seems to play a key role in the antidepressant-like action of these compounds. Dopamine release in the NAc shell is regulated by mGlu 2/3 receptors.
Smiles
C(O)(=O)[C@]1(F)[C@@]2([C@]1(C[C@@H](OCC3=CC(Cl)=C(Cl)C=C3)[C@]2(C(O)=O)N)[H])[H]
Molecular Formula
C15H14Cl2FNO5
Molecular Weight
378.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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