Lecozotan HCl
Product Specifications
CAS Number
433282-68-9
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9972
Bioactivity
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT (1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT (1A) receptor function.
Smiles
[C@H](CN(C(=O)C1=CC=C(C#N)C=C1)C2=CC=CC=N2)(C)N3CCN(C4=C5C(=CC=C4)OCCO5)CC3.Cl
Molecular Formula
C28H30ClN5O3
Molecular Weight
520.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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