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Lecozotan HCl

Product Specifications

CAS Number

433282-68-9

Target

5-HT Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Purity

0.9972

Bioactivity

Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT (1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT (1A) receptor function.

Smiles

[C@H](CN(C(=O)C1=CC=C(C#N)C=C1)C2=CC=CC=N2)(C)N3CCN(C4=C5C(=CC=C4)OCCO5)CC3.Cl

Molecular Formula

C28H30ClN5O3

Molecular Weight

520.02

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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