Labradimil
Product Specifications
CAS Number
159768-75-9
Target
Bradykinin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain. Labradimil increases carboplatin levels in brain tumors after pretreatment with dexamethasone.
Smiles
COc1ccc(C[C@@H](CN[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC(=O)[C@H](Cc2cccs2)NC(=O)CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](N)CCCNC(N)=N)cc1
Molecular Formula
C49H75N15O12S
Molecular Weight
1098.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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