KYA1797
Product Specifications
CAS Number
851304-36-4
Target
Others|||Kras|||Ras
Related Pathways
MAPK|||Others
Bioactivity
KYA1797 is an inhibitor of the Wnt/ß-catenin pathway. KYA1797 binds directly to the regulators of G-protein signaling domain of axin, initiats ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppresses the growth of CRCs harboring APC and KRAS mutations.
Smiles
OC(=O)CCN1C(=S)S\C(=C/C2=CC=C(O2)C2=CC=C(C=C2)[N+]([O-])=O)C1=O
Molecular Formula
C17H12N2O6S2
Molecular Weight
404.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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