Firazorexton (hydrate)
Firazorexton hydrate (TAK-994) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. Firazorexton hydrate can promote wakefulness and has the potential to improve narcolepsy-like symptoms in mice[1].
Product Specifications
CAS Number
[2861934-86-1]
Product Name Alternative
TAK-994
UNSPSC
12352005
Target
ERK; Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/firazorexton-hydrate.html
Purity
99.94
Solubility
10 mM in DMSO
Smiles
O=C(N(CC1)[C@H]([C@H]1N[S](C)(=O)=O)CC(C=CC=C2C3=CC(F)=CC(F)=C3)=C2F)C(C)(O)C.[1.5].O
Molecular Formula
C22H25F3N2O4S.3/2H2O
Molecular Weight
497.53
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
OX2 Receptor
Available Sizes
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