JNJ-42253432
Product Specifications
CAS Number
1428327-35-8
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
0.9998
Bioactivity
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.
Smiles
CN1CCc2c(C1)cccc2C(=O)NCC1(CCCCC1)N1CCN(CC1)c1ccccc1
Molecular Formula
C28H38N4O
Molecular Weight
446.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
039499-PE 200 µL
ORAI1, ID (ORAI1, CRACM1, TMEM142A, Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A) (PE) discontinued
Sign In for Pricing
View Details 
038599-ML490 100 µL
MRPL46, CT (MRPL46, C15orf4, LIECG2, 39S ribosomal protein L46, mitochondrial, P2ECSL) (MaxLight 490) discontinued
Sign In for Pricing
View Details 