JAK3i
Product Specifications
CAS Number
1918238-72-8
Target
JAK
Related Pathways
Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
>99.99%
Bioactivity
JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation.
Smiles
C(OCC)(=O)C=1C2=C(N=CN=C2NC1)C3=CC(NC(C=C)=O)=CC=C3F
Molecular Formula
C18H15FN4O3
Molecular Weight
354.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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