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JAK3i

Product Specifications

CAS Number

1918238-72-8

Target

JAK

Related Pathways

Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

>99.99%

Bioactivity

JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation.

Smiles

C(OCC)(=O)C=1C2=C(N=CN=C2NC1)C3=CC(NC(C=C)=O)=CC=C3F

Molecular Formula

C18H15FN4O3

Molecular Weight

354.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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