Israpafant
Product Specifications
CAS Number
117279-73-9
Target
PAFR, Others
Related Pathways
GPCR/G Protein, Others
Bioactivity
Israpafant is a selective antagonist for the platelet-activating factor receptor (IC50 = 0.84nM) . Israpafant inhibits PAF-induced human platelet aggregation. Israpafant inhibits the activation of eosinophil cells and consequently delays the development of immune responses. Israpafant also has anti-nephrotoxic properties and to mobilize calcium transport.
Smiles
CC=1N2C3=C(C(=NC(C)C2=NN1)C4=C(Cl)C=CC=C4)C=C(CCC5=CC=C(CC(C)C)C=C5)S3
Molecular Formula
C28H29ClN4S
Molecular Weight
489.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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