Avasimibe
Product Specifications
CAS Number
166518-60-1
Target
Cytochromes P450, Acyltransferase
Related Pathways
Metabolism
Purity
0.9991
Bioactivity
Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM) .
Smiles
CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C
Molecular Formula
C29H43NO4S
Molecular Weight
501.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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