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GX-936

Product Specifications

CAS Number

1235406-09-3

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

GX-936 (PF-05196233) is a selective Nav1.7 inhibitor that binds to the activated state of VSD4 (voltage-sensor domain IV), thereby opposing VSD4 inactivation and inhibiting Nav1.7. It can be used for pain perception research.

Smiles

N#CC1=CC(=CC=C1OC=2C=CC(=CC2C3=CC=NN3C4CN(CC)C4)C(F)(F)F)S(=O)(=O)NC5=NC=NS5

Molecular Formula

C24H20F3N7O3S2

Molecular Weight

575.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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