GW-3333
Product Specifications
CAS Number
212609-68-2
Target
Others, MMP, TNF
Related Pathways
Apoptosis, Proteases/Proteasome, Others
Bioactivity
GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF) -Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and TACE may prove therapeutic as antiarthritics.
Smiles
[C@@H]([C@@H](N(C=O)O)C(C)C)(C(N[C@H](C(NC1=CC=CC=N1)=O)[C@H](CC)C)=O)CC(C)C
Molecular Formula
C22H36N4O4
Molecular Weight
420.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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