Gue1654
Product Specifications
CAS Number
397290-30-1
Target
Others|||PKC|||NF-?B
Related Pathways
NF-?B|||Others|||Cytoskeletal Signaling|||Chromatin/Epigenetic
Purity
0.9831
Bioactivity
Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.Gue1654 inhibits OXE-R-inhibited protein kinase C-? (PKC-?) /nuclear factor ?B (NF-?B) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.
Smiles
O=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5
Molecular Formula
C23H17N3OS3
Molecular Weight
447.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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