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Gue1654

Product Specifications

CAS Number

397290-30-1

Target

Others|||PKC|||NF-?B

Related Pathways

NF-?B|||Others|||Cytoskeletal Signaling|||Chromatin/Epigenetic

Purity

0.9831

Bioactivity

Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.Gue1654 inhibits OXE-R-inhibited protein kinase C-? (PKC-?) /nuclear factor ?B (NF-?B) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.

Smiles

O=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5

Molecular Formula

C23H17N3OS3

Molecular Weight

447.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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