GSK-7227
Product Specifications
CAS Number
1067214-81-6
Target
Dehydrogenase, PPAR, PDK, CPT
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Metabolism
Purity
0.9917
Bioactivity
GSK-7227, a novel compound representing a novel class of peroxisome proliferator-activated receptor delta (PPARδ) partial agonists, demonstrates potent partial agonistic activity by upregulating the expression of PPARδ target genes, specifically carnitine palmitoyltransferase 1a (CPT1a) and pyruvate dehydrogenase kinase 4 (PDK4), in cultured skeletal muscle cells, indicating its potential role in modulating skeletal muscle metabolism and energy homeostasis.
Smiles
O=C(O)C1=CC(=CC=C1NC(=O)C2=CC=CC(=C2)S(=O)(=O)N3C=CC=4C3=CC=C(OC)C4C)C
Molecular Formula
C25H22N2O6S
Molecular Weight
478.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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