FR-181877
Product Specifications
CAS Number
172936-99-1
Target
Prostaglandin Receptor, Others
Related Pathways
Others, Immunology/Inflammation, GPCR/G Protein
Bioactivity
FR-181877, a nonprostanoid PGI2 agonist, inhibits ADP-induced aggregation of human platelets with an IC50 value of 0.081 microM and has high oral bioavailability (56%) with a long half-life (4.3 h) in rats.
Smiles
C(C1=NN(C[C@@H]2CC=3C(CC2)=C(OCC(O)=O)C=CC3)C(=O)C=C1)(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C30H28N2O4
Molecular Weight
480.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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