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FR-181877

Product Specifications

CAS Number

172936-99-1

Target

Prostaglandin Receptor, Others

Related Pathways

Others, Immunology/Inflammation, GPCR/G Protein

Bioactivity

FR-181877, a nonprostanoid PGI2 agonist, inhibits ADP-induced aggregation of human platelets with an IC50 value of 0.081 microM and has high oral bioavailability (56%) with a long half-life (4.3 h) in rats.

Smiles

C(C1=NN(C[C@@H]2CC=3C(CC2)=C(OCC(O)=O)C=CC3)C(=O)C=C1)(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C30H28N2O4

Molecular Weight

480.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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