FR-167356
Product Specifications
CAS Number
174185-16-1
Target
ATPase, Proton pump
Related Pathways
Membrane transporter/Ion channel
Purity
0.9974
Bioactivity
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H+-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.
Smiles
C(C)(C)(O)C=1C=2C(=C(NC(=O)C3=C(Cl)C=CC=C3Cl)C=CC2)OC1C
Molecular Formula
C19H17Cl2NO3
Molecular Weight
378.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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